Serum siderophilin in kwashiorkor.

نویسندگان

  • A U Antia
  • H McFarlane
  • J F Soothill
چکیده

Kwashiorkor is known to be associated with low plasma proteins (Edozien, 1960) and low serum ironbinding capacity (Edozien and Udeozo, 1960). Unpublished observations of Neale and Soothill (1958) confirmed that the iron-binding capacity was down to about one-third of a normal level, but showed that the siderophilin (syn. transferrin) was much more profoundly depressed-down to 6 mg./ 100 ml., compared with a normal European level of about 200. We therefore report a study of the serum siderophilin concentration estimated immunochemically in a series of children with typical kwashiorkor and of some control data. These values are correlated with a clinical grading of the severity of the disease and the effect of treatment.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Serum protein and transferrin determinations to distinguish kwashiorkor from iron deficiency anaemia.

Masawe, A. E. J., and Rwabwogo-Atenyi, J. (1973). Archives of Disease in Childhood, 48, 927. Serum protein and transferrin determinations to distinguish kwashiorkor from iron deficiency anaemia. Serum proteins and serum transferrin levels were studied in 38 African children of whom 10 were normal controls, 18 had severe iron deficiency anaemia, and 10 had kwashiorkor. The results showed that th...

متن کامل

Serum cholesterol esterifying activity in kwasiorkor.

Serum lipid levels were determined in 30 children with kwashiorkor and in 30 healthy children of comparable age. The serum concentrations of unesterified and esterified cholesterol, albumin and the cholesterol esterifying activity (CEA) were also measured in children with kwashiorkor before treatment and after recovery. All serum lipid fractions were significantly lower in kwashiorkor than in t...

متن کامل

The binding of thiopentone to kwashiorkor serum.

The binding of thiopentone to normal and kwashiorkor serum has been investigated. It has been confirmed that thiopentone is bound to albumin predominantly. In kwashiorkor serum, less binding to albumin occurs, but secondary binding sites appear. The significance of these observations is discussed.

متن کامل

Serum iron, total iron-binding capacity, and percentage saturation in normal subjects.

The serum iron was determined in 60 normal subjects (38 males and 22 females) with a mean age of 32.0 and 36.2 years respectively. The plasma total iron-binding capacity (TIBC) was also determined in 54 of these subjects (32 males and 22 females). Serum iron and TIBC determinations were performed between 8.45 am and 9.15 am. The mean serum iron concentration is 138.3 +/- 4.3 mug/100 ml (SD +/- ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Archives of disease in childhood

دوره 43 230  شماره 

صفحات  -

تاریخ انتشار 1968